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Non-H3 CDR template selection in antibody modeling through machine learning

Antibodies are proteins generated by the adaptive immune system to recognize and counteract a plethora of pathogens through specific binding. This adaptive binding is mediated by structural diversity in the six complementary determining region (CDR) loops (H1, H2, H3, L1, L2 and L3), which also make...

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Publicat a:PeerJ
Autors principals: Long, Xiyao, Jeliazkov, Jeliazko R., Gray, Jeffrey J.
Format: Artigo
Idioma:Inglês
Publicat: PeerJ Inc. 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6330961/
https://ncbi.nlm.nih.gov/pubmed/30648015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.6179
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