Landscape of Tumor Mutation Load, Mismatch Repair Deficiency, and PD-L1 Expression in a Large Patient Cohort of Gastrointestinal Cancers

The efficacy of immunotherapy varies widely among different gastrointestinal cancers. Response to immune checkpoint inhibitors is shown to correlate with tumor mutation load (TML), mismatch repair deficiency (dMMR) status, and programmed cell death-ligand 1 (PD-L1) expression. Herein, we quantify TM...

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Detaylı Bibliyografya
Yayımlandı:Mol Cancer Res
Asıl Yazarlar: Salem, Mohamed E., Puccini, Alberto, Grothey, Axel, Raghavan, Derek, Goldberg, Richard M., Xiu, Joanne, Korn, W. Michael, Weinberg, Benjamin A., Hwang, Jimmy J., Shields, Anthony F., Marshall, John L., Philip, Philip A., Lenz, Heinz-Josef
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6833953/
https://ncbi.nlm.nih.gov/pubmed/29523759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-17-0735
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