Landscape of Tumor Mutation Load, Mismatch Repair Deficiency, and PD-L1 Expression in a Large Patient Cohort of Gastrointestinal Cancers

The efficacy of immunotherapy varies widely among different gastrointestinal cancers. Response to immune checkpoint inhibitors is shown to correlate with tumor mutation load (TML), mismatch repair deficiency (dMMR) status, and programmed cell death-ligand 1 (PD-L1) expression. Herein, we quantify TM...

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Bibliografiset tiedot
Julkaisussa:Mol Cancer Res
Päätekijät: Salem, Mohamed E., Puccini, Alberto, Grothey, Axel, Raghavan, Derek, Goldberg, Richard M., Xiu, Joanne, Korn, W. Michael, Weinberg, Benjamin A., Hwang, Jimmy J., Shields, Anthony F., Marshall, John L., Philip, Philip A., Lenz, Heinz-Josef
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2018
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6833953/
https://ncbi.nlm.nih.gov/pubmed/29523759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-17-0735
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