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A Change in Bile Flow: Looking Beyond Transporter Inhibition in the Development of Drug-induced Cholestasis
BACKGROUND: Drug-induced Liver Injury (DILI) has received increasing attention over the past decades, as it represents the leading cause of drug failure and attrition. One of the most prevalent and severe forms of DILI involves the toxic accumulation of bile acids in the liver, known as Drug-induced...
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| Publicat a: | Curr Drug Metab |
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| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6833946/ https://ncbi.nlm.nih.gov/pubmed/31288715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1389200220666190709170256 |
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