miR-149-3p reverses CD8(+) T-cell exhaustion by reducing inhibitory receptors and promoting cytokine secretion in breast cancer cells

Blockade of inhibitory receptors (IRs) is one of the most effective immunotherapeutic approaches to treat cancer. Dysfunction of miRNAs is a major cause of aberrant expression of IRs and contributes to the immune escape of cancer cells. How miRNAs regulate immune checkpoint proteins in breast cancer...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Open Biol
Main Authors: Zhang, Meng, Gao, Dian, Shi, Yanmei, Wang, Yifan, Joshi, Rakesh, Yu, Qiongfang, Liu, Daheng, Alotaibi, Faizah, Zhang, Yujuan, Wang, Hongmei, Li, Qing, Zhang, Zhu-Xu, Koropatnick, James, Min, Weiping
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6833224/
https://ncbi.nlm.nih.gov/pubmed/31594465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.190061
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados