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Differential Pathogenicity of SHIV KB9 and 89.6 Env Correlates with Bystander Apoptosis Induction in CD4+ T cells

SHIV variants KB9 and 89.6 show differential pathogenesis in primate models with KB9 causing rapid CD4 decline while 89.6 failing to induce disease. We attempted to determine whether the differential pathogenicity of KB9 versus 89.6 was a result of differential bystander apoptosis inducing potential...

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Dettagli Bibliografici
Pubblicato in:Viruses
Autori principali: Mehmetoglu-Gurbuz, Tugba, Joshi, Anjali, Garg, Himanshu
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6832477/
https://ncbi.nlm.nih.gov/pubmed/31581579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v11100911
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