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Altered Bystander Apoptosis Induction and Pathogenesis of Enfuvirtide-Resistant HIV Type 1 Env Mutants

In previous studies on mechanisms of HIV-1-mediated pathogenesis we showed that bystander apoptosis mediated by cell surface-expressed HIV-1 Env correlated with the fusogenic properties of the gp41 subunit of Env. A crucial step in HIV gp41-mediated fusion is the refolding of the protein into a six-...

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Detalhes bibliográficos
Main Authors: Garg, Himanshu, Joshi, Anjali, Blumenthal, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2791676/
https://ncbi.nlm.nih.gov/pubmed/19619009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2009.0010
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