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Differential Pathogenicity of SHIV KB9 and 89.6 Env Correlates with Bystander Apoptosis Induction in CD4+ T cells

SHIV variants KB9 and 89.6 show differential pathogenesis in primate models with KB9 causing rapid CD4 decline while 89.6 failing to induce disease. We attempted to determine whether the differential pathogenicity of KB9 versus 89.6 was a result of differential bystander apoptosis inducing potential...

詳細記述

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書誌詳細
出版年:Viruses
主要な著者: Mehmetoglu-Gurbuz, Tugba, Joshi, Anjali, Garg, Himanshu
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6832477/
https://ncbi.nlm.nih.gov/pubmed/31581579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v11100911
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