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Vaso-Occlusion in Sickle Cell Disease: Is Autonomic Dysregulation of the Microvasculature the Trigger?

Sickle cell disease (SCD) is an inherited hemoglobinopathy characterized by polymerization of hemoglobin S upon deoxygenation that results in the formation of rigid sickled-shaped red blood cells that can occlude the microvasculature, which leads to sudden onsets of pain. The severity of vaso-occlus...

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Detalhes bibliográficos
Publicado no:J Clin Med
Main Authors: Veluswamy, Saranya, Shah, Payal, Denton, Christopher C., Chalacheva, Patjanaporn, Khoo, Michael C. K., Coates, Thomas D.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6832215/
https://ncbi.nlm.nih.gov/pubmed/31618931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm8101690
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