Progressive vasoconstriction with sequential thermal stimulation indicates vascular dysautonomia in sickle cell disease

Persons with sickle cell disease (SCD) exhibit subjective hypersensitivity to cold and heat perception in experimental settings, and triggers such as cold exposure are known to precipitate vaso-occlusive crises by still unclear mechanisms. Decreased microvascular blood flow (MBF) increases the likel...

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Vydáno v:Blood
Hlavní autoři: Veluswamy, Saranya, Shah, Payal, Khaleel, Maha, Thuptimdang, Wanwara, Chalacheva, Patjanaporn, Sunwoo, John, Denton, Christopher C., Kato, Roberta, Detterich, Jon, Wood, John C., Sposto, Richard, Khoo, Michael C. K., Zeltzer, Lonnie, Coates, Thomas D.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2020
Témata:
Red Cells, Iron, and Erythropoiesis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7472716/
https://ncbi.nlm.nih.gov/pubmed/32518948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2020005045
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