Sickle Cell Disease Subjects Have a Distinct Abnormal Autonomic Phenotype Characterized by Peripheral Vasoconstriction With Blunted Cardiac Response to Head-Up Tilt

In sickle cell disease (SCD), prolonged capillary transit times, resulting from reduced peripheral blood flow, increase the likelihood of rigid red cells entrapment in the microvasculature, predisposing to vaso-occlusive crisis. Since changes in peripheral flow are mediated by the autonomic nervous...

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Dades bibliogràfiques
Publicat a:Front Physiol
Autors principals: Chalacheva, Patjanaporn, Kato, Roberta M., Shah, Payal, Veluswamy, Saranya, Denton, Christopher C., Sunwoo, John, Thuptimdang, Wanwara, Wood, John C., Detterich, Jon A., Coates, Thomas D., Khoo, Michael C. K.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2019
Matèries:
Physiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6470196/
https://ncbi.nlm.nih.gov/pubmed/31031633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2019.00381
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