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Iduronate-2-Sulfatase-Regulated Dermatan Sulfate Levels Potentiate the Invasion of Breast Cancer Epithelia through Collagen Matrix

Cancer epithelia show elevation in levels of sulfated proteoglycans including dermatan sulfates (DS). The effect of increased DS on cancer cell behavior is still unclear. We hypothesized that decreased expression of the enzyme Iduronate-2-sulfatase (IDS) can lead to increased DS levels, which would...

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Detalles Bibliográficos
Publicado en:J Clin Med
Autores principales: Singh, Vishal, Jha, Keshav Kumar, M, Jyothsna K., Kumar, Rekha V., Raghunathan, Varun, Bhat, Ramray
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6832158/
https://ncbi.nlm.nih.gov/pubmed/31574977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm8101562
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