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Iduronate-2-Sulfatase-Regulated Dermatan Sulfate Levels Potentiate the Invasion of Breast Cancer Epithelia through Collagen Matrix

Cancer epithelia show elevation in levels of sulfated proteoglycans including dermatan sulfates (DS). The effect of increased DS on cancer cell behavior is still unclear. We hypothesized that decreased expression of the enzyme Iduronate-2-sulfatase (IDS) can lead to increased DS levels, which would...

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Detalhes bibliográficos
Publicado no:J Clin Med
Main Authors: Singh, Vishal, Jha, Keshav Kumar, M, Jyothsna K., Kumar, Rekha V., Raghunathan, Varun, Bhat, Ramray
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6832158/
https://ncbi.nlm.nih.gov/pubmed/31574977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm8101562
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