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High Fidelity Deep Sequencing Reveals No Effect of ATM, ATR, and DNA-PK Cellular DNA Damage Response Pathways on Adenovirus Mutation Rate

Most DNA viruses exhibit relatively low rates of spontaneous mutation. However, the molecular mechanisms underlying DNA virus genetic stability remain unclear. In principle, mutation rates should not depend solely on polymerase fidelity, but also on factors such as DNA damage and repair efficiency....

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Risso-Ballester, Jennifer, Sanjuán, Rafael
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6832117/
https://ncbi.nlm.nih.gov/pubmed/31614688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v11100938
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