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Genome-Wide Estimation of the Spontaneous Mutation Rate of Human Adenovirus 5 by High-Fidelity Deep Sequencing

Rates of spontaneous mutation determine the ability of viruses to evolve, infect new hosts, evade immunity and undergo drug resistance. Contrarily to RNA viruses, few mutation rate estimates have been obtained for DNA viruses, because their high replication fidelity implies that new mutations typica...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Risso-Ballester, Jennifer, Cuevas, José M., Sanjuán, Rafael
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5100877/
https://ncbi.nlm.nih.gov/pubmed/27824949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006013
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