Myc‐dependent endothelial proliferation is controlled by phosphotyrosine 1212 in VEGF receptor‐2

Exaggerated signaling by vascular endothelial growth factor (VEGF)‐A and its receptor, VEGFR2, in pathologies results in poor vessel function. Still, pharmacological suppression of VEGFA/VEGFR2 may aggravate disease. Delineating VEGFR2 signaling in vivo provides strategies for suppression of specifi...

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Bibliografiske detaljer
Udgivet i:EMBO Rep
Main Authors: Testini, Chiara, Smith, Ross O, Jin, Yi, Martinsson, Pernilla, Sun, Ying, Hedlund, Marie, Sáinz‐Jaspeado, Miguel, Shibuya, Masabumi, Hellström, Mats, Claesson‐Welsh, Lena
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
Fag:
Reports
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6832004/
https://ncbi.nlm.nih.gov/pubmed/31545012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201947845
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