Myc‐dependent endothelial proliferation is controlled by phosphotyrosine 1212 in VEGF receptor‐2

Exaggerated signaling by vascular endothelial growth factor (VEGF)‐A and its receptor, VEGFR2, in pathologies results in poor vessel function. Still, pharmacological suppression of VEGFA/VEGFR2 may aggravate disease. Delineating VEGFR2 signaling in vivo provides strategies for suppression of specifi...

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Enregistré dans:
Détails bibliographiques
Publié dans:EMBO Rep
Auteurs principaux: Testini, Chiara, Smith, Ross O, Jin, Yi, Martinsson, Pernilla, Sun, Ying, Hedlund, Marie, Sáinz‐Jaspeado, Miguel, Shibuya, Masabumi, Hellström, Mats, Claesson‐Welsh, Lena
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2019
Sujets:
Reports
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6832004/
https://ncbi.nlm.nih.gov/pubmed/31545012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201947845
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