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Identification of mutations in Malaysian patients with argininosuccinate lyase (ASL) deficiency

Argininosuccinate lyase (ASL) deficiency impairs the function of the urea cycle that detoxifies blood ammonia in the body. Mutation that occurs in the ASL gene is the cause of occurrence of ASL deficiency (ASLD). This deficiency causes hyperammonemia, hepatopathy and neurodevelopmental delay in pati...

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Bibliografiska uppgifter
I publikationen:Mol Genet Metab Rep
Huvudupphovsmän: Ali, Ernie Zuraida, Yakob, Yusnita, Ngu, Lock Hock
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6831900/
https://ncbi.nlm.nih.gov/pubmed/31709144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgmr.2019.100525
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