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Identification of mutations in Malaysian patients with argininosuccinate lyase (ASL) deficiency

Argininosuccinate lyase (ASL) deficiency impairs the function of the urea cycle that detoxifies blood ammonia in the body. Mutation that occurs in the ASL gene is the cause of occurrence of ASL deficiency (ASLD). This deficiency causes hyperammonemia, hepatopathy and neurodevelopmental delay in pati...

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Bibliografske podrobnosti
izdano v:Mol Genet Metab Rep
Main Authors: Ali, Ernie Zuraida, Yakob, Yusnita, Ngu, Lock Hock
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6831900/
https://ncbi.nlm.nih.gov/pubmed/31709144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgmr.2019.100525
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