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Disruption of the mouse Shmt2 gene confers embryonic anaemia via foetal liver-specific metabolomic disorders
In a previous study, we proposed that age-related mitochondrial respiration defects observed in elderly subjects are partially due to age-associated downregulation of nuclear-encoded genes, including serine hydroxymethyltransferase 2 (SHMT2), which is involved in mitochondrial one-carbon (1C) metabo...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6831688/ https://ncbi.nlm.nih.gov/pubmed/31690790 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-52372-6 |
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