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The use of micelles to deliver potential hedgehog pathway inhibitor for the treatment of liver fibrosis
Rationale: Hedgehog (Hh) pathway plays an essential role in liver fibrosis by promoting the proliferation of hepatic stellate cells (HSCs) by enhancing their metabolism via yes-associated protein 1 (YAP1). Despite the presence of several inhibitors, Hh signaling cannot be controlled exclusively due...
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| Veröffentlicht in: | Theranostics |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Ivyspring International Publisher
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6831471/ https://ncbi.nlm.nih.gov/pubmed/31695785 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.38913 |
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