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Codelivery of Small Molecule Hedgehog Inhibitor and miRNA for Treating Pancreatic Cancer
Successful treatment of pancreatic ductal adenocarcinoma (PDAC) remains a challenge due to the desmoplastic microenvironment that promotes both tumor growth and metastasis and forms a barrier to chemotherapy. Hedgehog (Hh) signaling is implicated in initiation and progression of PDAC and also contri...
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| Publicado en: | Mol Pharm |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4829351/ https://ncbi.nlm.nih.gov/pubmed/25679326 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp500847s |
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