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Therapeutic Potential of OMe-PS-miR-29b1 for Treating Liver Fibrosis

Trans-differentiation of quiescent hepatic stellate cells (HSCs) into active myofibroblasts secretes excess amounts of extracellular matrix (ECM) proteins. miR-29b1 has the potential to treat liver fibrosis, because it targets several profibrotic genes. We previously demonstrated that miR-29b1 and t...

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Detalles Bibliográficos
Publicado en:Mol Ther
Autores principales: Kumar, Virender, Kumar, Vinod, Luo, Jiangtao, Mahato, Ram I.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Gene & Cell Therapy 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6277432/
https://ncbi.nlm.nih.gov/pubmed/30287074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2018.08.022
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