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Therapeutic Potential of OMe-PS-miR-29b1 for Treating Liver Fibrosis
Trans-differentiation of quiescent hepatic stellate cells (HSCs) into active myofibroblasts secretes excess amounts of extracellular matrix (ECM) proteins. miR-29b1 has the potential to treat liver fibrosis, because it targets several profibrotic genes. We previously demonstrated that miR-29b1 and t...
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| Veröffentlicht in: | Mol Ther |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society of Gene & Cell Therapy
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6277432/ https://ncbi.nlm.nih.gov/pubmed/30287074 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2018.08.022 |
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