Genome-wide discovery and validation of diagnostic DNA methylation-based biomarkers for hepatocellular cancer detection in circulating cell free DNA

Hepatocellular carcinoma (HCC), the most prevalent form of liver cancer, is growing in incidence but treatment options remain limited, particularly for late stage disease. As liver cirrhosis is the principal risk state for HCC development, markers to detect early HCC within this patient population a...

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Bibliografiske detaljer
Udgivet i:Theranostics
Main Authors: Hlady, Ryan A., Zhao, Xia, Pan, Xiaoyu, Yang, Ju Dong, Ahmed, Fowsiyo, Antwi, Samuel O., Giama, Nasra H., Patel, Tushar, Roberts, Lewis R., Liu, Chen, Robertson, Keith D.
Format: Artigo
Sprog:Inglês
Udgivet: Ivyspring International Publisher 2019
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Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6831291/
https://ncbi.nlm.nih.gov/pubmed/31695765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.35573
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