Genome-wide discovery and validation of diagnostic DNA methylation-based biomarkers for hepatocellular cancer detection in circulating cell free DNA

Hepatocellular carcinoma (HCC), the most prevalent form of liver cancer, is growing in incidence but treatment options remain limited, particularly for late stage disease. As liver cirrhosis is the principal risk state for HCC development, markers to detect early HCC within this patient population a...

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Vydáno v:Theranostics
Hlavní autoři: Hlady, Ryan A., Zhao, Xia, Pan, Xiaoyu, Yang, Ju Dong, Ahmed, Fowsiyo, Antwi, Samuel O., Giama, Nasra H., Patel, Tushar, Roberts, Lewis R., Liu, Chen, Robertson, Keith D.
Médium: Artigo
Jazyk:Inglês
Vydáno: Ivyspring International Publisher 2019
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6831291/
https://ncbi.nlm.nih.gov/pubmed/31695765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.35573
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