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Procyanidin B2 prevents lupus nephritis development in mice by inhibiting NLRP3 inflammasome activation

Lupus nephritis (LN) is a multifactorial event that contributes to the long-term mortality of systemic lupus erythematosus (SLE). Activation of NLRP3 inflammasome has been known to play a role in SLE pathogenesis. We evaluated the renal protection effects of procyanidin B2 (PCB2) and the involvement...

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Bibliographic Details
Published in:Innate Immun
Main Authors: He, Junhui, Sun, Mingchong, Tian, Sujian
Format: Artigo
Language:Inglês
Published: SAGE Publications 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6830913/
https://ncbi.nlm.nih.gov/pubmed/29874961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1753425918780985
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