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Pharmacological Npt2a Inhibition Causes Phosphaturia and Reduces Plasma Phosphate in Mice with Normal and Reduced Kidney Function

BACKGROUND: The kidneys play an important role in phosphate homeostasis. Patients with CKD develop hyperphosphatemia in the later stages of the disease. Currently, treatment options are limited to dietary phosphate restriction and oral phosphate binders. The sodium-phosphate cotransporter Npt2a, whi...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Am Soc Nephrol
मुख्य लेखकों: Thomas, Linto, Xue, Jianxiang, Murali, Sathish Kumar, Fenton, Robert A., Dominguez Rieg, Jessica A., Rieg, Timo
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society of Nephrology 2019
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6830793/
https://ncbi.nlm.nih.gov/pubmed/31409727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2018121250
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