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PF-06869206 is a selective inhibitor of renal P(i) transport: evidence from in vitro and in vivo studies
Plasma phosphate (P(i)) levels are tightly controlled, and elevated plasma P(i) levels are associated with an increased risk of cardiovascular complications and death. Two renal transport proteins mediate the majority of P(i) reabsorption: Na(+)-phosphate cotransporters Npt2a and Npt2c, with Npt2a a...
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| Udgivet i: | Am J Physiol Renal Physiol |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Physiological Society
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7509280/ https://ncbi.nlm.nih.gov/pubmed/32744087 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00146.2020 |
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