PF-06869206 is a selective inhibitor of renal P(i) transport: evidence from in vitro and in vivo studies

Plasma phosphate (P(i)) levels are tightly controlled, and elevated plasma P(i) levels are associated with an increased risk of cardiovascular complications and death. Two renal transport proteins mediate the majority of P(i) reabsorption: Na(+)-phosphate cotransporters Npt2a and Npt2c, with Npt2a a...

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發表在:Am J Physiol Renal Physiol
Main Authors: Thomas, Linto, Xue, Jianxiang, Tomilin, Viktor N., Pochynyuk, Oleh M., Dominguez Rieg, Jessica A., Rieg, Timo
格式: Artigo
語言:Inglês
出版: American Physiological Society 2020
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7509280/
https://ncbi.nlm.nih.gov/pubmed/32744087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00146.2020
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