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ATM Dysfunction in Pancreatic Adenocarcinoma and Associated Therapeutic Implications

Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal solid malignancies with very few therapeutic options to treat advanced or metastatic disease. The utilization of genomic sequencing has identified therapeutically relevant alterations in ~25% of PDAC patients, most notably in the...

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Detalhes bibliográficos
Publicado no:Mol Cancer Ther
Main Authors: Armstrong, Samantha A., Shultz, Christopher W., Azimi-Sadjadi, Ariana, Brody, Jonathan R., Pishvaian, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6830515/
https://ncbi.nlm.nih.gov/pubmed/31676541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-19-0208
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