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ATM Dysfunction in Pancreatic Adenocarcinoma and Associated Therapeutic Implications

Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal solid malignancies with very few therapeutic options to treat advanced or metastatic disease. The utilization of genomic sequencing has identified therapeutically relevant alterations in ~25% of PDAC patients, most notably in the...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Cancer Ther
Hauptverfasser: Armstrong, Samantha A., Shultz, Christopher W., Azimi-Sadjadi, Ariana, Brody, Jonathan R., Pishvaian, Michael J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6830515/
https://ncbi.nlm.nih.gov/pubmed/31676541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-19-0208
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