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Desmoplasia in pancreatic ductal adenocarcinoma: insight into pathological function and therapeutic potential

Extensive desmoplasia is a prominent feature of the pancreatic ductal adenocarcinoma (PDAC) microenvironment. Initially, studies demonstrated that desmoplasia promotes proliferation, invasion and chemoresistance in PDAC cells. While these findings suggested the therapeutic potential of targeting des...

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Detalhes bibliográficos
Publicado no:Genes Cancer
Main Authors: Cannon, Andrew, Thompson, Christopher, Hall, Bradley R., Jain, Maneesh, Kumar, Sushil, Batra, Surinder K.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6086006/
https://ncbi.nlm.nih.gov/pubmed/30108679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/genesandcancer.171
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