Desmoplasia in pancreatic ductal adenocarcinoma: insight into pathological function and therapeutic potential

Extensive desmoplasia is a prominent feature of the pancreatic ductal adenocarcinoma (PDAC) microenvironment. Initially, studies demonstrated that desmoplasia promotes proliferation, invasion and chemoresistance in PDAC cells. While these findings suggested the therapeutic potential of targeting des...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Genes Cancer
Prif Awduron: Cannon, Andrew, Thompson, Christopher, Hall, Bradley R., Jain, Maneesh, Kumar, Sushil, Batra, Surinder K.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Impact Journals LLC 2018
Pynciau:
Review
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6086006/
https://ncbi.nlm.nih.gov/pubmed/30108679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/genesandcancer.171
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