Desmoplasia in pancreatic ductal adenocarcinoma: insight into pathological function and therapeutic potential

Extensive desmoplasia is a prominent feature of the pancreatic ductal adenocarcinoma (PDAC) microenvironment. Initially, studies demonstrated that desmoplasia promotes proliferation, invasion and chemoresistance in PDAC cells. While these findings suggested the therapeutic potential of targeting des...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Genes Cancer
Asıl Yazarlar: Cannon, Andrew, Thompson, Christopher, Hall, Bradley R., Jain, Maneesh, Kumar, Sushil, Batra, Surinder K.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2018
Konular:
Review
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6086006/
https://ncbi.nlm.nih.gov/pubmed/30108679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/genesandcancer.171
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