The Deubiquitinating Enzyme Inhibitor PR-619 Enhances the Cytotoxicity of Cisplatin via the Suppression of Anti-Apoptotic Bcl-2 Protein: In Vitro and In Vivo Study

After chemotherapy for the treatment of metastatic bladder urothelial carcinoma (UC), most patients inevitably encounter drug resistance and resultant treatment failure. Deubiquitinating enzymes (DUBs) remove ubiquitin from target proteins and play a critical role in maintaining protein homeostasis....

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cells
Päätekijät: Kuo, Kuan-Lin, Liu, Shing-Hwa, Lin, Wei-Chou, Chow, Po-Ming, Chang, Yu-Wei, Yang, Shao-Ping, Shi, Chung-Sheng, Hsu, Chen-Hsun, Liao, Shih-Ming, Chang, Hong-Chiang, Huang, Kuo-How
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI 2019
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6830310/
https://ncbi.nlm.nih.gov/pubmed/31627336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8101268
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