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Toward G protein-coupled receptor structure-based drug design using X-ray lasers
Rational structure-based drug design (SBDD) relies on the availability of a large number of co-crystal structures to map the ligand-binding pocket of the target protein and use this information for lead-compound optimization via an iterative process. While SBDD has proven successful for many drug-di...
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| Vydáno v: | IUCrJ |
|---|---|
| Hlavní autoři: | , , , , , , , , , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
International Union of Crystallography
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6830214/ https://ncbi.nlm.nih.gov/pubmed/31709066 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2052252519013137 |
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