Toward G protein-coupled receptor structure-based drug design using X-ray lasers

Rational structure-based drug design (SBDD) relies on the availability of a large number of co-crystal structures to map the ligand-binding pocket of the target protein and use this information for lead-compound optimization via an iterative process. While SBDD has proven successful for many drug-di...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:IUCrJ
Egile Nagusiak: Ishchenko, Andrii, Stauch, Benjamin, Han, Gye Won, Batyuk, Alexander, Shiriaeva, Anna, Li, Chufeng, Zatsepin, Nadia, Weierstall, Uwe, Liu, Wei, Nango, Eriko, Nakane, Takanori, Tanaka, Rie, Tono, Kensuke, Joti, Yasumasa, Iwata, So, Moraes, Isabel, Gati, Cornelius, Cherezov, Vadim
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: International Union of Crystallography 2019
Gaiak:
Research Papers
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6830214/
https://ncbi.nlm.nih.gov/pubmed/31709066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2052252519013137
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