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Cell ratcheting through the Sbf RabGEF directs force balancing and stepped apical constriction

During Drosophila melanogaster gastrulation, the invagination of the prospective mesoderm is driven by the pulsed constriction of apical surfaces. Here, we address the mechanisms by which the irreversibility of pulsed events is achieved while also permitting uniform epithelial behaviors to emerge. W...

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Dettagli Bibliografici
Pubblicato in:J Cell Biol
Autori principali: Miao, Hui, Vanderleest, Timothy E., Jewett, Cayla E., Loerke, Dinah, Blankenship, J. Todd
Natura: Artigo
Lingua:Inglês
Pubblicazione: Rockefeller University Press 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6829657/
https://ncbi.nlm.nih.gov/pubmed/31562231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201905082
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