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Cell ratcheting through the Sbf RabGEF directs force balancing and stepped apical constriction

During Drosophila melanogaster gastrulation, the invagination of the prospective mesoderm is driven by the pulsed constriction of apical surfaces. Here, we address the mechanisms by which the irreversibility of pulsed events is achieved while also permitting uniform epithelial behaviors to emerge. W...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Principais autores: Miao, Hui, Vanderleest, Timothy E., Jewett, Cayla E., Loerke, Dinah, Blankenship, J. Todd
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6829657/
https://ncbi.nlm.nih.gov/pubmed/31562231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201905082
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