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A protective role for N-acylphosphatidylethanolamine phospholipase D in 6-OHDA-induced neurodegeneration

N-acylphosphatidylethanolamine phospholipase D (NAPE-PLD) catalyzes the cleavage of membrane NAPEs into bioactive fatty-acid ethanolamides (FAEs). Along with this precursor role, NAPEs might also serve autonomous signaling functions. Here, we report that injections of 6-hydroxydopamine (6-OHDA) into...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Palese, Francesca, Pontis, Silvia, Realini, Natalia, Piomelli, Daniele
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2019
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6828692/
https://ncbi.nlm.nih.gov/pubmed/31685899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-51799-1
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