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Targeting PDGFRα-activated glioblastoma through specific inhibition of SHP-2–mediated signaling
BACKGROUND: Glioblastoma (GBM) is the most malignant primary brain tumor, with dismal median survival. Treatment of GBM is particularly challenging given the intrinsic resistance to chemotherapy and difficulty of drugs to reach the tumor beds due to the blood–brain barrier. Here, we examined the eff...
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| Publicado no: | Neuro Oncol |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6827835/ https://ncbi.nlm.nih.gov/pubmed/31232447 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz107 |
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