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AGO unchained: Canonical and non-canonical roles of Argonaute proteins in mammals

Argonaute (AGO) proteins play key roles in animal physiology by binding to small RNAs and regulating the expression of their targets. In mammals, they do so through two distinct pathways: the miRNA pathway represses genes through a multiprotein complex that promotes both decay and translational repr...

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Detalhes bibliográficos
Publicado no:Front Biosci (Landmark Ed)
Main Authors: Sala, Laura, Chandrasekhar, Srividya, Vidigal, Joana A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6827344/
https://ncbi.nlm.nih.gov/pubmed/31585876
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