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Non-canonical roles of canonical telomere binding proteins in cancers

Reactivation of telomerase is a major hallmark observed in 90% of all cancers. Yet paradoxically, enhanced telomerase activity does not correlate with telomere length and cancers often possess short telomeres; suggestive of supplementary non-canonical roles that telomerase might play in the developm...

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Библиографические подробности
Опубликовано в: :Cell Mol Life Sci
Главные авторы: Akincilar, Semih Can, Chan, Claire Hian Tzer, Ng, Qin Feng, Fidan, Kerem, Tergaonkar, Vinay
Формат: Artigo
Язык:Inglês
Опубликовано: Springer International Publishing 2021
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8164586/
https://ncbi.nlm.nih.gov/pubmed/33599797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-021-03783-0
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