Apalutamide Sensitizes Prostate Cancer to Ionizing Radiation via Inhibition of Non-Homologous End-Joining DNA Repair

Androgen-deprivation therapy was shown to improve treatment outcome of external beam radiation therapy (EBRT) for locally advanced prostate cancer (PCa). DNA damage response (DDR) was suggested to play a role in the underlying mechanism, but conflicting results were reported. This study aims to reve...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Cancers (Basel)
Asıl Yazarlar: Zhang, Wenhao, Liao, Chen-Yi, Chtatou, Hajar, Incrocci, Luca, van Gent, Dik C., van Weerden, Wytske M., Nonnekens, Julie
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6827010/
https://ncbi.nlm.nih.gov/pubmed/31635359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11101593
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