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STAT3 and STAT5 Activation in Solid Cancers

The Signal Transducer and Activator of Transcription (STAT)3 and 5 proteins are activated by many cytokine receptors to regulate specific gene expression and mitochondrial functions. Their role in cancer is largely context-dependent as they can both act as oncogenes and tumor suppressors. We review...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Igelmann, Sebastian, Neubauer, Heidi A., Ferbeyre, Gerardo
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6826753/
https://ncbi.nlm.nih.gov/pubmed/31557897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11101428
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