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Molecular Detection of Minimal Residual Disease before Allogeneic Stem Cell Transplantation Predicts a High Incidence of Early Relapse in Adult Patients with NPM1 Positive Acute Myeloid Leukemia
We analyzed the impact of alloHSCT in a single center cohort of 89 newly diagnosed NPM1(mut) AML patients, consecutively treated according to the Northern Italy Leukemia Group protocol 02/06 [NCT00495287]. After two consolidation cycles, the detection of measurable residual disease (MRD) by RQ-PCR w...
Salvato in:
| Pubblicato in: | Cancers (Basel) |
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| Autori principali: | , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
MDPI
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6826431/ https://ncbi.nlm.nih.gov/pubmed/31569375 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11101455 |
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