Capture-Based Next-Generation Sequencing Improves the Identification of Immunoglobulin/T-Cell Receptor Clonal Markers and Gene Mutations in Adult Acute Lymphoblastic Leukemia Patients Lacking Molecular Probes

The monitoring of minimal residual disease (MRD) in Philadelphia-negative acute lymphoblastic leukemia (ALL) requires the identification at diagnosis of immunoglobulin/T-cell receptor (Ig/TCR) rearrangements as clonality markers. Aiming to simplify and possibly improve the patients’ initial screenin...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Cavagna, Roberta, Guinea Montalvo, Marie L., Tosi, Manuela, Paris, Michela, Pavoni, Chiara, Intermesoli, Tamara, Bassan, Renato, Mosca, Andrea, Rambaldi, Alessandro, Spinelli, Orietta
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7352935/
https://ncbi.nlm.nih.gov/pubmed/32526928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12061505
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