Molecular Detection of Minimal Residual Disease before Allogeneic Stem Cell Transplantation Predicts a High Incidence of Early Relapse in Adult Patients with NPM1 Positive Acute Myeloid Leukemia

We analyzed the impact of alloHSCT in a single center cohort of 89 newly diagnosed NPM1(mut) AML patients, consecutively treated according to the Northern Italy Leukemia Group protocol 02/06 [NCT00495287]. After two consolidation cycles, the detection of measurable residual disease (MRD) by RQ-PCR w...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Lussana, Federico, Caprioli, Chiara, Stefanoni, Paola, Pavoni, Chiara, Spinelli, Orietta, Buklijas, Ksenija, Michelato, Anna, Borleri, GianMaria, Algarotti, Alessandra, Micò, Caterina, Grassi, Anna, Intermesoli, Tamara, Rambaldi, Alessandro
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6826431/
https://ncbi.nlm.nih.gov/pubmed/31569375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11101455
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