Targeting of copper-trafficking chaperones causes gene-specific systemic pathology in Drosophila melanogaster: prospective expansion of mutational landscapes that regulate tumor resistance to cisplatin

Copper, a transition metal, is an essential component for normal growth and development. It acts as a critical co-factor of many enzymes that play key roles in diverse cellular processes. The present study attempts to investigate the regulatory functions decisively controlling copper trafficking dur...

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Detalles Bibliográficos
Publicado en:Biol Open
Main Authors: Theotoki, Eleni I., Velentzas, Athanassios D., Katarachia, Stamatia A., Papandreou, Nikos C., Kalavros, Nikolas I., Pasadaki, Sofia N., Giannopoulou, Aikaterini F., Giannios, Panagiotis, Iconomidou, Vassiliki A., Konstantakou, Eumorphia G., Anastasiadou, Ema, Papassideri, Issidora S., Stravopodis, Dimitrios J.
Formato: Artigo
Idioma:Inglês
Publicado: The Company of Biologists Ltd 2019
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6826294/
https://ncbi.nlm.nih.gov/pubmed/31575544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.046961
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