Targeting of copper-trafficking chaperones causes gene-specific systemic pathology in Drosophila melanogaster: prospective expansion of mutational landscapes that regulate tumor resistance to cisplatin

Copper, a transition metal, is an essential component for normal growth and development. It acts as a critical co-factor of many enzymes that play key roles in diverse cellular processes. The present study attempts to investigate the regulatory functions decisively controlling copper trafficking dur...

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Bibliografiska uppgifter
I publikationen:Biol Open
Huvudupphovsmän: Theotoki, Eleni I., Velentzas, Athanassios D., Katarachia, Stamatia A., Papandreou, Nikos C., Kalavros, Nikolas I., Pasadaki, Sofia N., Giannopoulou, Aikaterini F., Giannios, Panagiotis, Iconomidou, Vassiliki A., Konstantakou, Eumorphia G., Anastasiadou, Ema, Papassideri, Issidora S., Stravopodis, Dimitrios J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Company of Biologists Ltd 2019
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6826294/
https://ncbi.nlm.nih.gov/pubmed/31575544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.046961
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